關於「NLRP3 ASC」標籤，搜尋引擎有相關的訊息討論：

The NLRP3 Inflammasome: An Overview of Mechanisms of ... - NCBI。

2019年7月6日 · The pyrin domain of NLRP3 interacts with the pyrin domain of ASC to initiate ... Kuijpers T.W., van den Berg T.K. Human NLRP3 inflammasome ...。

Regulation of NLRP3 Inflammasome by Phosphorylation - NCBI。

2018年10月8日 · ASC, apoptosis-associated speck-like protein containing a CARD; BTK, Bruton's tyrosine kinase; EP4, E-prostanoid 4; IKK, IκB kinase; JNK1, c-Jun ...。

SARS-CoV-2 N protein promotes NLRP3 inflammasome activation ...。

2021年8月2日 · The indicated proteins in cell extract were analyzed by WB. d HEK293T cells were co-transfected with plasmids encoding NLRP3, ASC, pro-Caspase-1 ...。

A phenotypic high-content, high-throughput screen identifies ...。

2021年7月28日 · Our high-content screening assay yielded robust assay metrics and identified a number of inhibitors of NLRP3-dependent ASC speck formation, ...。

The ASC Speck and NLRP3 Inflammasome Function Are Spatially ...。

2021年7月19日 · Herein we report that the NLRP3:ASC speck is not required for nigericin-induced inflammasome activation, but facilitates and maximizes IL-1β ...。

Chloride regulates dynamic NLRP3-dependent ASC oligomerization ...。

2018年10月2日 · Formed after Cl− efflux exclusively, ASC specks are NLRP3 dependent, ... G.L.-C. is funded by Wellcome Trust and the Royal Society (Grant ...： tw | tw。

Cellular Models and Assays to Study NLRP3 Inflammasome Biology。

An intact and functional NACHT domain is required for interaction with ASC, activation of caspase-1, and IL-1β release in THP-1 cells [37]. Of note, mutations ...： tw | tw。

Role of the NLRP3 inflammasome in cancer。

2018年11月17日 · The inflammasome complex consists of a Nod-like receptor (NLR), the adapter apoptosis-associated speck-like (ASC) protein, and Caspase-1.。

Syk is involved in NLRP3 inflammasome‐mediated caspase‐1 ...。

2015年1月20日 · Syk increases NLRP3 inflammasome formation through phosphorylation of ASC and enhancement of ASC oligomerization. NLRP3 is the most crucial ...。

Isoliquiritigenin is a potent inhibitor of NLRP3 inflammasome ...。

2014年9月10日 · Share on. Email; Facebook; Twitter; Linked In; Reddit; Wechat ... Moreover, GL inhibited NLRP3- and AIM2-activated ASC oligomerization, ...